Growth Factors

Recombinant long Arg3 analogue of insulin-like growth factor 1

IGF-1 LR3 is a recombinant analogue of insulin-like growth factor 1 with an N-terminal extension and an arginine substitution at position 3. The modifications reduce binding to IGFBPs (IGF binding proteins) and prolong activity, making LR3 IGF-1 a common reagent in cell-culture and animal-physiology research. It is not approved for human use.

Research and biomanufacturing literature; veterinary in vivo studies; no human therapeutic approval

Mechano-growth factor — alternatively spliced IGF-1 isoform (IGF-1Ec) E-domain peptide

MGF is the E-domain peptide of the IGF-1Ec splice variant. The full-length IGF-1Ec transcript is upregulated in muscle in response to mechanical stress, and synthetic E-domain peptides have been studied for effects on muscle satellite cells, cartilage, and peripheral nerves in rodent and in vitro models.

Preclinical (rodent and in vitro) literature

Naturally occurring actin-binding peptide

Thymosin Beta-4 (Tβ4) is a 43-residue actin-binding peptide expressed in many human tissues. Published research spans in vitro cell-biology assays, rodent models, human-organoid work, and a small number of early-phase clinical studies (e.g., in ophthalmology and cardiovascular research).

Cell biology, rodent, and early-phase clinical literature